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Importantly, such a status also facilitates the gradual emergence of hepatoprotective effects of traditional Chinese medicines (TCMs), such as Si Miao Formula, Jiangzhi Granules, Liushen Capsules, Chaihu-Shugan Power, Cassiae Semen and Gynostemma, as well as some natural products (NPs), including Costunolide, Coprinus comatus polysaccharide, Antarctic krill oil, Oridonin and Berberine, both at the basic exploration and clinical research levels