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Mounjaro (tirzepatide) is a dual GIP/GLP-1 receptor agonist licensed for type 2 diabetes treatment in adults L-carnitine is an amino acid derivative that transports fatty acids into mitochondria for energy production No documented pharmacokinetic or pharmacodynamic interactions exist between L-carnitine and tirzepatide Both substances can cause gastrointestinal side effects including nausea, vomiting, and diarrhoea Always inform your prescribing clinician about all supplements before combining them with prescription medications Regular monitoring of blood glucose, HbA1c, and kidney function remains essential when taking Mounjaro Table of Contents What Are L-Carnitine and Mounjaro

It is important to note that women of childbearing age should be on contraception while on ACEi or ARBs and guidelines recommend stopping these agents if pregnancy were to occur due to their teratogenic effects (17, 18)

FIGURE 3 TABLE 2 Outcomes of pancreatitis associated with the use of GLP-1 RA