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In October 2023, A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) trial assessing the effect of semaglutide versus placebo on the progression of renal impairment in people with T2DM and chronic kidney disease was stopped prematurely due to results of an interim analysis showing significant efficacy of semaglutide with full results due to be released in the first half of 2024 [39]
Inducing a calorie deficit that often results in rapid weight loss
Anyone with a personal or family history of medullary thyroid carcinoma or MEN 2 (a boxed-warning contraindication), a history of pancreatitis, or serious hypersensitivity to semaglutide
Fortunately, there are plenty of over-the-counter products that can help with GLP-1 constipation
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