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Listen to GNL Podcast Episode 14: Overcoming Insulin Resistance

The exact mechanism isnt fully understood, but its likely related to electrolyte changes from reduced food intake, dehydration, or the medications direct effects on muscle tissue

Strategies to Minimize Weight Rebound When Medication Changes If discontinuation becomes necessary, gradual tapering (rather than abrupt stopping) allows your body to adjust metabolic signaling over 8-12 weeks instead of days

Under this tightly observed protocol, in motivated patients with type 1 diabetes, under close clinical supervision (and by whatever mechanisms of action 14-17 ), significant weight reduction occurred without metabolic destabilisation