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In rat embryonic myocytes with hypoxia/reoxygenation, trimetazidine pre-treatment mitigated the increase in oxidative stress proteins such as lactate dehydrogenase and ROS [169]

Benchoam, D., Cuevasanta, E., Roman, J

Why Addressing the Nervous System Is Essential If the nervous system is not addressed, pain may: Spread beyond the original injury site Return quickly after medications wear off Worsen during stress or fatigue Become resistant to escalating interventions This helps explain why chronic pain frequently persists despite normal imaging, laboratory results, or repeated structural treatments