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The 2024 Lancet Commission on dementia prevention, intervention, and care updated its model to include 14 modifiable risk factors and estimated that roughly 45% of dementia cases may be delayed or reduced if those risks are addressed across the lifespan

Along with the heterogeneity of the disease and the lack of reliable biomarkers, the problem for developing specific treatments for PD is its multiple pathophysiological mechanisms, many of which are common to the mechanisms of T2DM development, including brain insulin resistance, impaired energy and glucose metabolism, mitochondrial dysfunction, chronic systemic inflammation, neuroinflammation, impaired lysosome function, and oxidative stress [56, 57]

Why breakthrough GLP-1 weight loss pills may be a bad thing for employer insurance coverage

Kang, J