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Their mode of action is inclusive of increasing release of insulin in a glucose-dependent manner, thereby lowering the risk of hypoglycemia as compared to the other anti-diabetic agents

Patients with pre-existing liver disease or gallbladder dysfunction require closer monitoring

A recent systematic review identified 33 registered trials looking at GLP-1s for SUDs, predominantly for alcohol and nicotine, but with growing interest in opioid and stimulant SUDs

Plasma GPx activity was higher in CD patients compared to controls, but the differences were not seen in patients with inactive CD, without signs of disease symptoms (21)