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If the increased demand is not met by the increased thiamine supply, a state of TD may easily follow, first in enterocytes, and after some period at the level of organism, most often manifested as Wernicke encephalopathy (145147)

These trace minerals often become depleted during healing periods when demands increase

The percentage is based on comparative animal studies measuring tensile strength recovery, histological organization, and macroscopic tissue closure at standardized post-injury time points

It has been shown that co-supplementation with these nutrients enhances cognitive function and offers neuroprotective benefits, thus highlighting the need for future investigation