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Reduced glutamate receptors, presynaptic neurotransmitter proteins, and postsynaptic functional proteins in the PFC and hippocampus were also observed ( Figure 2 ) (Zhao et al., 2012

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Half of the mice did not receive G49 and were distributed in groups receiving: vehicle (HFD), GCGR antagonist (H + GCGRant), GLP-1R antagonist (H + Ex9-39) and the 2 antagonists (H + Ex9-39 + GCGRant)

Glutathione boosts the utilization and recycling of other antioxidants, namely vitamin C, E, alpha lipoic acid and CoQ10. NAC is able to increase cell protection against oxidative stress which is accomplished through the release of cysteine, which is the rate-limiting precursor in the synthesis of glutathione