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Like any effective medication, side effects are possible, often mild gastrointestinal symptoms

HamiltonA,HolscherC.Receptors for the incretin glucagn like peptide-1 are expressed on neurons in the central nervous system.Neuroreport2009;20:1161-6

Concerns about the potential association between certain diabetes medications and cardiovascular disease meant that in 2010 the FDA approved liraglutide on condition that Novo Nordisk conduct a post-marketing study to evaluate the drug's effect on the incidence of major cardiovascular events (Nielsen, DeChiaro, Goldman)