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That is what we have started this week with tirzepatide. Trial protocols call for half of the 1,000 participants to receive a placebo, inert doses that have no effect, rather than the active drug, creating a control group that is critical to obtaining scientifically valid results

It filled a genuine gap when GLP-1s were impossible to find, and it continues to serve patients with needs that FDA-approved medications cant meet

Wang G, Meyer JG, Cai W, Softic S, Li ME, Verdin E, et al