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They are sold strictly as research chemicals, and no claims regarding skin appearance, cosmetic effect, or any other outcome in humans are made or implied by this article, in line with MHRA regulations under the Human Medicines Regulations 2012

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MiR-146a-5p is reported to modulate immune response and reduce inflammation by targeting both TRAF6 and interleukin-1 receptor-associated kinase 1 (IRAK1) IRAK1 in macrophages, and astrocytes