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Watch your spots for signs of infection, such as: Pain around the spot Pus or oozing liquid that persists A strong odor from the wound Inflammation, redness, and swelling A fever Worsening appearance of the wound If you have any of these symptoms, talk to your doctor right away

Methods Search Strategy and Study Selection The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist was inspected for the systematic review ( Tables S1, S2 , respectively

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Never mix pharmaceutical products outside of a compounding pharmacy environment