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The article says no significant metabolic slowdown has been reported in the first month

This means a doctor will likely prescribe a low dose to start and then slowly increase the amount of Topamax a patient takes until reaching the dosage that works best for the patient

10.1038/cdd.2009.163 82 PetermannI.TriggsC

Ascorbic Acid (Vitamin C) Injection Ascorbic Acid (Vitamin C) Injection (Preservative Free) (30 mL Vial) Ascorbic Acid (Vitamin C) Injection (Preserved) (30 mL Vial) Product Overview Ascorbic Acid (Vitamin C) Injection is a compounded sterile injectable solution formulated for parenteral administration, designed to deliver high concentrations of vitamin C directly into the bloodstream