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Animals 13(7):1223 Donoso FS (2018) Chronic disease as risk multiplier for disadvantage

Deficiencies in mitochondrial GR activity have been implicated in various neurodegenerative conditions, aging processes, and metabolic disorders

Reduced cardio-renal function accounts for most of the in-hospital morbidity and mortality risk among patients with type 2 diabetes undergoing primary percutaneous coronary intervention for st-segment elevation myocardial infarction