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Semaglutide therapy activates GLP-1 receptors throughout the digestive system, which can slow gastric emptying and alter how your body absorbs certain nutrients, particularly vitamin B12

147,148 The detrimental effects of hypoxia are exacerbated by hypertension also inducing kidney tissue to generate elevated levels of reactive oxygen species such as superoxide, hydrogen peroxide, peroxynitrite, and hydroxyl radicals

A: It can reflect increased training capacity, glycogen/water shifts, appetite changes, or lean mass gain rather than pure fat gain

The buttocks, trunk, chest, face, and distal extremities can also be involved