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As expected, treatment with DEM, started at 72 hours after knock-down initiation, leads to a significantly reduced response compared to siCtrl (Fig 3A)

We first validated the buffering phenotype in the follow-up studies, in which SLC25A19 exhibited milder growth fitness defect compared to the control cells in the presence of complex III inhibitor antimycin, complex I inhibitor piericidin and complex V inhibitor oligomycin than in the regular culture condition (Supplementary Fig

Second, TAZ attenuates Treg cell development by reducing Tip60-mediated acetylation of Foxp3

Standard glutathione supplements often struggle with this