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Decreased hypertrophic cell size is associated with increased TSC2 To begin to address the mechanisms for the decreased size of the hypertrophic chondrocytes in the CartIR / mice, we determined the expression of TSC1 and TSC2 proteins in chondrocytes

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This cellular damage can contribute to impairments such as the inability to repair DNA, reduced supply of oxygen and nutrients to the cells, cell mutations, and consequent cell death

The squeeze fell hardest on Gen X, where 59% of considerers pointed to cost, compared with 48% of Gen Z and 42% of millennials