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The use of claim 21 wherein the PDE-5 inhibitor is for use by oral administration

Vitamin B12 supplements are typically derived from two sources: cyanocobalamin or methylcobalamin

The purpose of medication, when appropriate, is not to replace healthy habits

The signs and symptoms of Carnitine-Acylcarnitine Translocase Deficiency Disorder may include: Atrioventricular block Bradycardia Cardiorespiratory arrest Elevated serum creatine phosphokinase Generalized hypotonia Hypoglycemia Ventricular extrasystoles Ventricular hypertrophy Very frequently present symptoms in 80-99% of the cases: Abnormality of skeletal muscles Cardiomyopathy Decreased plasma carnitine Dicarboxylic aciduria Elevated creatine kinase after exercise Elevated hepatic transaminases Elevated plasma acylcarnitine levels Encephalopathy Fasting hypoglycemia Hepatomegaly Hyperammonemia Hypoketotic hypoglycemia Hypotension Irritability Lethargy Respiratory insufficiency Rhabdomyolysis Ventricular tachycardia Frequently present symptoms in 30-79% of the cases: Coma Occasionally present symptoms in 5-29% of the cases: Cyanosis Hepatic failure Hypothermia Microcephaly Nystagmus Oliguria Preeclampsia Seizures Sudden episodic apnea (Source: Carnitine-Acylcarnitine Translocase Deficiency