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semaglutide in patients with heart failure with preserved ejection fraction and obesity

An analysis of published CeA single-nucleus RNA sequencing data revealed that Glp1r -expressing neurons co-express GABAergic markers, lack glutamatergic markers and cluster with CeA neurons that express the vitamin D receptor, Vdr 39 (Supplementary Fig

We also discuss NRF2-based molecular programs that may govern stem cell state and function with age, and implications of this for age-related pathologies