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R.WangT.WangC.et al
TranDCDangALHoangTNLNguyenCTLeTMPDinhTNMet alPrevalence of thalassemia in the Vietnamese population and building a clinical decision support system for prenatal screening for thalassemia
However, in resistant patients, oxidative stress causes a conformational change in Keap1, leading to the release of NRF2, which translocates to the nucleus and binds to antioxidant response element (ARE), activating the expression of downstream antioxidant genes, including GPX4, NQO1, HO-1 and SOD1 [33], and promoting the synthesis of GSH, as illustrated in Fig
This is consistent with our previous study demonstrating that, at the 2-week timepoint, exposure to low BPA at 72 hpf and vehicle at 7 dpf reduced larval survival, while low BPA at 7 dpf had no effect 42
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