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672,673 DFO treatment significantly reduces iron accumulation in brain tissue and BMECs, increases brain capillary density, and improves cerebral blood flow and behavioral performance

Post-transcriptional and post-translational regulation of central carbon metabolic enzymes in cancer

Gilam et al

it competitively binds to cellular receptors, blocking the body's natural active B6 and potentially inducing a functional deficiency that leads to peripheral neuropathy (nerve tingling and pain)