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Therefore, critically analyzing negative clinical results is necessary to avoid misleading conclusions, standardize the clinical relevance of endpoint indicators, and promote the rational development of the antiaging field

doi:10.1073/pnas.1301816110 Mazza A, Cicero AF, Ramazzina E, et al

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The absence of systematic monitoring is one of the most common shortcomings in patient-initiated peptide use, and it is precisely what differentiates responsible clinical supervision from unsupervised self-experimentation