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Proinflammatory cytokines TNF- and IL1- activate the canonical NF-B pathway that induce the gene expression of cyclooxigenase-2, inducible nitric oxide synthase-3, inflammatory cytokines, and matrix metalloproteinases [75] These changes lead to the damage of TJs, decreased endothelial integrity and increased permeability at the BBB [73, 76], and to neuroinflammation and the development of chronic neurodegenerative diseases such as AD [10, 77]

The brand even says its not suitable during that time, and frankly, I wouldnt mess around with antioxidant-heavy supplements when your hormones are already in flux

Consult your doctor Not enough scientific data is available on using Glowriance Sugar Free Orange Flavour Chewable Tablet on pregnant women

Try to relax