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Curcumin and Liver Disease: from Chemistry to Medicine

This suppression is independent of plasma cholesterol changes and BW reduction through regulating markers of plaque instability and inflammation including those linked to plaque hemorrhage (CD163), matrix turnover (matrix metalloproteinase (MMP)-3, MMP-13), cholesterol metabolism (prostaglandin I2 synthase (PTGIS), ATP-binding cassette transporter 1 (ABCA1)), leukocyte recruitment (C-C motif chemokine ligand 2 (CCL2), osteopontin (OPN), interleukin (IL)-6), and leukocyte rolling, extravasation and adhesion (vascular cell adhesion molecule (VCAM)-1, E-selectin (SELE)) [16]

If appropriate following a medical evaluation, treatment recommendations may be discussed and ongoing follow-up care may be provided through telehealth

The study authors are adamant that their research doesn't justify health care providers' prescribing semaglutide off-label for smoking cessation