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While dexamethasone only modestly reduced synovial inflammation, it failed to prevent cartilage deterioration, whereas liraglutide significantly enhanced pain thresholds, lowered synovial scores, and preserved cartilage integrity, with 60 g doses notably reducing overall joint damage [140]

Their pioneering modes of action coupled with early triumphs imply that these agents may soon emerge as essential elements in overcoming challenges posed by obesity and diabetes across patient populations

(2019) 30:98796.e6

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