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The presence of a peak at 1,098 Da in the HRMS data (Supplementary Figure S6) corresponding to the fragment expected from cleavage of the amide bond between Lys17 and Ala18 further confirms trypsins enzymatic efficiency, as its activity depends on pH, temperature, and peptide structure

Due to its lipophilic nature, resveratrol can bind to lipoprotein particles, which seems crucial for its antioxidant effects (155)

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