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TM6SF2: a novel genetic player in nonalcoholic fatty liver and cardiovascular disease
Using in vitro systems and animal based models, these studies have focused on characterizing receptor specificity, intracellular signaling fidelity, and the temporal organization of hormone secretion
The SOCS1-mimicking peptide reduced lupus-like symptoms in mouse models, demonstrating the potential to regulate an immune response that runs on overdrive
DJ-1 is highly conserved across species and typically exists in the cytoplasm but can translocate to the nucleus and mitochondria under oxidative stress
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