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FIGURE 8 3.8 Immunohistochemical findings The immunohistochemical investigation demonstrated a significant increase in expression of proapoptotic makers, Bax, and caspase-3, in MTX treated group, which was associated with decreased antiapoptotic marker, Bcl-2, expression when compared to the CTRL group (Figure 9)

Avoid over-exercising, which can trigger histamine release

Same lighting conditions, camera angle, hair styling (or lack thereof), and time of day reduce variability that masks or exaggerates apparent changes

Winter SC, Szabo-Aczel S, Curry CJ, Hutchinson HT, Hogue R, Shug A: Plasma carnitine deficiency