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A surprising effect on smoking Among participants who also smoked, those on semaglutide reported a greater decline in cigarette use compared to the placebo group

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The ability of glucagon to increase energy expenditure was first demonstrated in rats in 1960 [57] and was subsequently confirmed in different species including humans [58], although one study reported that glucagon infusion over 72 h did not increase energy expenditure in healthy individuals with overweight or obesity [59]