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NCCN has been pleased to collaborate with ASCO on developing strategies and collaborative guidelines for managing the toxicity of immunotherapies." Immunotherapy-related side effects can occur at any time and can affect any organ

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doi:10.1096/fj.02-0216fje Mogi M, Togari A, Tanaka K, Ogawa N, Ichinose H, Nagatsu T (1999) Increase in level of tumor necrosis factor (TNF)-alpha in 6-hydroxydopamine-lesioned striatum in rats without influence of systemic L-DOPA on the TNF-alpha induction

The FDA has also warned that SARMs can have serious side effects including an increased risk of stroke [27]