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BTBR mice showed suppressed hippocampal neurogenesis, but curcumin restored progenitor proliferation and enhanced neural differentiation, suggesting that early curcumin exposure exerts long-lasting benefits (Zhong et al., 2020)

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PMID: 15883756 Patel P, Saadabadi A

Given their widespread use and overall safety profile, DPP-4 inhibitors remain a first-line or second-line treatment for many Japanese individuals with type 2 diabetes, though careful monitoring is warranted in specific high-risk populations