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187 In head and neck squamous cell carcinoma (HNSCC), phosphorylated STAT3 can directly bind to the ARG1 promoter region of MDSCs to promote transcription, thereby contributing to the immunosuppressive effect of MDSCs

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In the pivotal SURPASS clinical trial program evaluating tirzepatide for type 2 diabetes, and the SURMOUNT trials for weight management, gastrointestinal adverse effects were frequently reported