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A comprehensive literature search was performed in PubMed, Web of Science, Embase, and Scopus from inception to October 2025 using the keywords tirzepatide, GLP-1/GIP receptor agonist, obstructive sleep apnea, and obesity. Priority was given to randomized controlled trials, major observational studies, and relevant mechanistic research

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Drosophila aux orchestrates the phosphorylation-dependent assembly of the lysosomal V-ATPase in glia and contributes to SNCA/alpha-synuclein degradation