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[1] [4] When to seek medical attention: Contact your healthcare provider immediately if you experience: Severe or persistent vomiting, signs of dehydration (dizziness, decreased urination) Severe abdominal pain, especially if radiating to your back (may indicate pancreatitis) Right upper abdominal pain, fever, or yellowing of skin/eyes (possible gallbladder disease) Decreased urine output or swelling (potential kidney problems) Neck mass, hoarseness, or difficulty swallowing (thyroid tumor warning signs) Severe allergic reactions including swelling of face/lips/tongue or difficulty breathing Visual changes (especially in patients with diabetic retinopathy) Symptoms of hypoglycemia (if taking insulin or sulfonylureas) Persistent nausea lasting beyond the first month or significantly impacting nutritional intake also warrants clinical evaluation

If a lesion visualised after tape stripping is much lighter (with regular structures), this is likely to be reassuring As discussed in the chapter Melanoma - an overview the dermoscopic examination of melanocytic lesions requires considerable experience In terms of benign and malignant lesions on the palms and soles refer to the chapter Melanoma: acral lentiginous melanoma