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reuteri also enhance antioxidant enzyme activities such as glutathione peroxidase, suppressing oxidative stress and stabilizing regulatory T cells by preventing ROS-dependent mTOR activation, which plays a role in immune regulation in lupus models (124)

Firstly, it can be displaced from the binding pocket by endogenous substrates, which consequently hinders its efficacy

Although newborn screening (NBS) using tandem mass spectrometry (MS/MS) enables early detection by measuring more than 40 metabolites in dried blood spots, including propionylcarnitine (C3), the C3/acetylcarnitine (C2) ratio, and methionine, metabolite-based screening may be less reliable in clinically unstable or stressed newborns [16]

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