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MD data has been submitted to Zenodo ( Markov state model The conformational space of p53 TAD2 was analyzed via Markov State Model (MSM) 62

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Immunohistochemical analysis also revealed a significant decrease in the hepatic expression of both proapoptotic markers Bax and caspase-3 with significant increase in antiapoptotic Bcl-2 expression in rats treated with NTZ-200, NAC or 4-PBA when compared to MTX group (Figure 9)