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The cases name Novo Nordisk, the manufacturer of Ozempic and Wegovy, and assert that the company knew or should have known about a connection between semaglutide and optic nerve damage based on clinical data, post marketing reports, and emerging medical research

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Results of the GO enrichment and KEGG analysis of these target genes suggested that they are mainly involved in the regulation of inflammatory response, apoptotic process, regulation of cell proliferation, neutrophil extracellular trap formation, arachidonic acid metabolism, phospholipase D, HIF-1, and VEGF signalling pathways