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In both instances, the time to reach maximum blood concentration was approximately three to four hours.[51] A different study found that intramuscular injections of rapamycin doses ranging from 0.01-0.08 mg/kg, either given once or daily over a seven-day treatment schedule, also resulted in measurable and clinically relevant blood concentrations of rapamycin

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The future perspectives section of this review was drafted with the assistance of GPT-4.0 (OpenAI), and the authors assume full responsibility for its final content, interpretation, and integration into the manuscript

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