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At this point, domperidone should be preferred over metoclopramide due to the risk of extrapyramidal side effects
Voltage-clamp electrophysiology verifies that the Na + - and carnitine-binding sites are coupled To further explore the carnitine and Na + binding sites, wildtype and mutant OCTN2 transporters were expressed in Xenopus laevis oocytes and two-electrode voltage-clamp electrophysiology was utilised to demonstrate the transport of carnitine is Na + -dependent
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The evidence is still early and largely from conference data rather than long-term trials, so I would not call these drugs a stone treatment
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