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Sleep quality is closely linked to body weight, and excess weight can contribute to poor sleep patterns, frequent waking, and reduced sleep depth
Tailored outreach methods may improve enrollment rates
Whilst pharmacological combinations remain clinically unsupported for retatrutide at this stage, there is robust evidence that certain lifestyle interventions can meaningfully complement weight-loss pharmacotherapy
(2025) trial specifically tested semaglutide as an add-on to AID systems and found a 4.8 percentage point improvement in time in range (from 69.4% to 74.2%) alongside an 11.3-unit daily reduction in insulin, without any increase in hypoglycemia
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