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In summary, artesunate inhibits the activation of M1 macrophages and the RIPK1/RIPK3/MLKL signaling cascade by down-regulating Mincle expression, consequently reducing both the inflammatory response and necroptosis, thereby ameliorating renal injury in AKI

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A Five-Year Prospective Study of Spinal Radiographic Progression and Its Predictors in Men and Women With Ankylosing Spondylitis