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Chlorogenic acid a hydroxycinnamic acid derivative abundant in artichoke inhibits glucose-6-phosphatase (reducing glucose availability for lipogenesis) and modulates PPAR- transcription, suppressing the gene expression programs driving new adipocyte formation
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However, these pathways were significantly less enriched when comparing the TB001-treated group with the syngeneic control, and the PPAR signaling and phospholipase D signaling pathways were no significant enriched ( Figure 4F )
And there were a couple of other really interesting little things you shared with me when we had an earlier chat, and one of those was iodine and its relationship with histamine
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