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However, long-term safety and efficacy data remain limited, and most weight loss programs still rely on GLP-1 monotherapy

It should be noted that while Ozempic and Mounjaro are officially approved for type 2 diabetes, they are also used off label for weight loss, as clinical trials have consistently shown that both produce significant weight loss as a secondary metabolic benefit

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The study found semaglutide reduced knee pain significantly more than the placebo