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Maintaining basal-bolus GLP-1 levels as a treatment approach These studies have clearly shown that MBS corrects post-prandial GLP-1 responses in people with obesity but does not improve fasting GLP-1 levels, which remain lower in some patients as compared to normal-weight individuals

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Remember the product-specific storage allowances: Unopened Wegovy may be kept at temperatures up to 86F (30C) for up to 28 days if refrigeration is not possible Ozempic, after first use, may be stored at temperatures up to 86F (30C) for up to 56 days Patients should never use semaglutide that has been frozen, even if it has subsequently thawed, as freezing causes irreversible protein denaturation

That schedule assumes average tolerability