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This release can be rapid, with a peak at 10 min post-initial glucose stimulus, followed by a sustained release from major insulin granules (approximately 9095%) lasting up to 60 min under normal conditions (15, 31)

Using expired medication may result in reduced therapeutic efficacy, as the active ingredient (semaglutide) may have degraded over time, potentially leading to inadequate glycaemic control

Incorporate resistance training with weights or bodyweight exercises 2-3 times weekly to build metabolically active muscle tissue and increase overall calorie burn