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Consistently, overexpression of SCD1 was correlated with the presence of mesenchymal markers in GC tissues, while GC cells demonstrated mesenchymal-to-epithelial transition phenotype after SCD1 downregulation

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This is particularly relevant as the BBB represents a major challenge in CNS drug delivery, often preventing neurotherapeutic agents from effectively reaching the brain

There are two separate tracks to keep in mind hereone for the CagriSema combination and one for cagrilintide as a standalone drug