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The gut microbiome in Alzheimer's disease: what we know and what remains to be explored

Treatment convenience directly impacts patient adherence and satisfaction rates, making oral supplementation more sustainable for long-term use while IV therapy suits acute interventions requiring rapid systemic delivery

RCM of two R -configurated amino acids forming an R ( i , i + 4) R (8) staple also proceeds efficiently, but this particular staple neither stabilizes helices well nor provides peptides with high cell-penetrating ability, and RCM reactions using one R - and one S -configurated amino acid are found to be very inefficient [83]

Residual alcohol in the vial can denature peptides on contact